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Description
BT20 cells were exposed to a non-targeting siRNA (Uni) or siRNA targeting NEK4. RNA was harvested, and RNASeq followed by GSEA was completed. We note that depleting NEK4 alone caused enhancement in cell cycle genes that was consistent with the increase in cell proliferation observed in the BT20 cells following knockdown.
Document Type
Dataset
Publication Date
2025
Publisher
New Mexico State University
Keywords
Biological Sciences, NEK4, p21, proliferation, RNAseq, Triple Negative Breast Cancer
Disciplines
Biochemistry | Biology | Chemistry
Department / Organizational Unit
Department of Chemistry & Biochemistry
Copyright Statement
Public Domain / CC0, no rights reserved
Funder
National Institute of General Medical Sciences
Grant / Award Number
P20GM103451
Recommended Citation
Ashley, Amanda, "Data from: NEK4 Suppresses Cell Proliferation in BT20 Triple-Negative Breast Cancer Cells by Diminishing Expression of Cell Cycle Genes, While Its Depletion Mitigates Proliferation in Other Cell Lines" (2025). Chemistry & Biochemistry: Datasets. 2.
https://digitalcommons.nmsu.edu/chem-biochem-data/2